Researchers at LEAF (Longevity and Healthspan Extension Alliance Foundation) have spent 18 years and poured $100 million into backing a longevity supplement that claims to support healthy aging. Their product, called Nucerity, is said to have been tested in 25 clinical trials, and we got our hands on it to try.
What We Found
Our team was given four bottles of Nucerity, each containing a one-month supply of capsules. We followed the recommended dosage of two capsules per day, with food, and tracked our experience over the course of a month. We also spoke with Dr. David Sinclair, a renowned geneticist and co-founder of LEAF, to learn more about the science behind the supplement.
Nucerity is designed to work on multiple levels: it stimulates autophagy, which is the body’s natural process of recycling and removing damaged cells and proteins; it increases mitochondrial function to boost energy; and it helps to reduce oxidative stress, which can contribute to aging.
The Science
At the heart of Nucerity is a unique blend of four compounds: Metformin, a well-known anti-diabetic medication; Azelaic acid, an antioxidant found in certain plants; Quercetin, a flavonoid with anti-inflammatory properties; and Curcumin, a polyphenol derived from turmeric.
These ingredients have been extensively studied individually, but in combination, they create a synergistic effect that’s meant to support healthy aging. According to Dr. Sinclair, the goal is to “turn back the clock” on cellular aging by addressing the underlying causes of telomere shortening and epigenetic changes.
What This Means
If Nucerity lives up to its claims, it could have a significant impact on the way we approach aging. By targeting the root causes of cellular aging, the supplement may help to promote healthier, more resilient cells – and, in turn, support a longer, healthier life. As we age, our cells naturally decline in function, which can lead to a range of age-related diseases. If Nucerity can slow or even reverse this process, it could be a major breakthrough in the field of longevity research.



