Millions of Britons Taking Glucosamine May Be at Higher Risk of Dementia, Says Study
A popular joint pain supplement, taken by millions of people in the UK, has been linked to a higher risk of dementia, according to a major new study. Researchers in the US found that glucosamine, commonly used to ease joint pain and inflammation, may be associated with an increased risk of cognitive decline.
The study, which analyzed data from over 1,000 participants, suggests that long-term glucosamine use may have an unintended consequence: accelerating the development of dementia.
How Does Glucosamine Work, and Could It Affect Brain Health?
Glucosamine is a naturally occurring compound found in cartilage, the connective tissue that cushions joints. As people age, cartilage breaks down, leading to joint pain and inflammation. Taking glucosamine supplements is thought to help slow this process, reducing joint pain and stiffness.
However, researchers believe that glucosamine may also have an impact on brain health. The study found that glucosamine use was associated with changes in the brain’s microstructure, which could contribute to cognitive decline. Exactly how glucosamine affects the brain is still unclear, but some experts speculate that it may interact with the gut-brain axis, influencing the production of neurotransmitters and hormones that regulate cognitive function.
Should You Stop Taking Glucosamine?
While the study’s findings are concerning, experts caution against panicking. The increased risk of dementia was observed in people who took high doses of glucosamine for extended periods. Most people take glucosamine for joint pain, not dementia prevention, and the risks associated with long-term use are still uncertain.
What this means: If you’re taking glucosamine for joint pain, don’t stop taking it without consulting your doctor. However, consider discussing alternative options, such as exercise, weight management, or other supplements like omega-3 fatty acids or turmeric, which may have anti-inflammatory effects without the potential dementia risk.
